Apa saja klasifikasi TB resisten obat?

Mono-resistant TB: Resistant to one first-line anti-TB drug only.

Isoniazid-resistant TB: Resistant to Isoniazid, but susceptible to Rifampicin.

Poly-resistant TB: Resistant to more than one first-line anti-TB drug, excluding both Isoniazid and Rifampicin.

Rifampicin-resistant TB (RR): Resistance to rifampicin detected using phenotypic or genotypic methods, with or without resistance to other anti-TB drugs. Includes mono-resistance, poly-resistance, MDR, or XDR.

Multidrug-resistant TB (MDR-TB): Resistant to at least both Isoniazid and Rifampicin.

Pre-extensively drug-resistant TB: Resistant to Rifampicin, Isoniazid, and either Fluoroquinolones or one injectable drug (Amikacin or Kanamycin).

Extensively drug-resistant TB (XDR-TB): Resistance to any fluoroquinolone, and at least one of three second-line injectable drugs (capreomycin, kanamycin, or amikacin), in addition to being multidrug-resistant.

Sumber: Wulandari, D.A., Hartati, Y.W., Ibrahim, A.U. and Pitaloka, D.A.E., 2024. Multidrug-resistant tuberculosis. Clinica Chimica Acta, 559, p.119701.

Editor: Yoseph Samodra